[HTML][HTML] Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
G Chen, J Cizeau, CV Velde, JH Park, G Bozek… - Journal of Biological …, 1999 - ASBMB
We have identified Nix, a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein
Nip3. Human and murine Nix have a 56 and 53% amino acid identity to human and murine
Nip3, respectively. The carboxyl terminus of Nix, including a transmembrane domain, is
highly homologous to Nip3 but it bears a longer and distinct asparagine/proline-rich N
terminus. Human Nip3 maps to chromosome 14q11. 2–q12, whereas Nix/BNip3L was found
on 8q21. Nix encodes a 23.8-kDa protein but it is expressed as a 48-kDa protein, suggesting …
Nip3. Human and murine Nix have a 56 and 53% amino acid identity to human and murine
Nip3, respectively. The carboxyl terminus of Nix, including a transmembrane domain, is
highly homologous to Nip3 but it bears a longer and distinct asparagine/proline-rich N
terminus. Human Nip3 maps to chromosome 14q11. 2–q12, whereas Nix/BNip3L was found
on 8q21. Nix encodes a 23.8-kDa protein but it is expressed as a 48-kDa protein, suggesting …