[HTML][HTML] Analysis of 4-1BBL and laminin binding to murine 4-1BB, a member of the tumor necrosis factor receptor superfamily, and comparison with human 4-1BB

DT Loo, NJ Chalupny, J Bajorath, WW Shuford… - Journal of Biological …, 1997 - ASBMB
The T cell activation antigen 4-1BB (CDw137) is a distantly related member of the tumor
necrosis factor receptor family of cell surface receptors. We previously reported that murine 4-
1BB (m4-1BB) bound to extracellular matrix (ECM) proteins. Recently, a tumor necrosis
factor-like ligand of m4-1BB, m4-1BBL, as well as the human counterparts of 4-1BB (ILA)
and 4-1BBL (h4-1BB and h4-1BBL, respectively) have been cloned. No information is
currently available on how binding of m4-1BB to ECM proteins affects its binding to m4 …