Genome organization and transactivation of the human immunodeficiency virus type 2
M Guyader, M Emerman, P Sonigo, F Clavel… - Nature, 1987 - nature.com
M Guyader, M Emerman, P Sonigo, F Clavel, L Montagnier, M Alizon
Nature, 1987•nature.comAbstract Analysis of the nucleotide sequence of the human retrovirus associated with AIDS
in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized
HIV-1. We suggest that these viruses existed long before the current AIDS epidemics. Their
biological properties are conserved in spite of limited sequence homology; this may help the
determination of the structure–function relationships of the different viral elements.
in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized
HIV-1. We suggest that these viruses existed long before the current AIDS epidemics. Their
biological properties are conserved in spite of limited sequence homology; this may help the
determination of the structure–function relationships of the different viral elements.
Abstract
Analysis of the nucleotide sequence of the human retrovirus associated with AIDS in West Africa, HIV-2, shows that it is evolutionary distant from the previously characterized HIV-1. We suggest that these viruses existed long before the current AIDS epidemics. Their biological properties are conserved in spite of limited sequence homology; this may help the determination of the structure–function relationships of the different viral elements.
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