Role of macrophage migration inhibitory factor in hepatitis B virus-specific cytotoxic-T-lymphocyte-induced liver injury
K Kimura, M Nagaki, J Nishihira, S Satake… - Clinical and vaccine …, 2006 - Am Soc Microbiol
K Kimura, M Nagaki, J Nishihira, S Satake, K Kuwata, H Moriwaki
Clinical and vaccine immunology, 2006•Am Soc MicrobiolMacrophage migration inhibitory factor (MIF) plays a pivotal role in the development of
various inflammatory diseases. Here, we found that anti-mouse MIF antibody treatment
reduced liver injury and inflammatory cell infiltration into the liver after injection of antigen-
specific cytotoxic T lymphocytes into hepatitis B virus transgenic mice.
various inflammatory diseases. Here, we found that anti-mouse MIF antibody treatment
reduced liver injury and inflammatory cell infiltration into the liver after injection of antigen-
specific cytotoxic T lymphocytes into hepatitis B virus transgenic mice.
Abstract
Macrophage migration inhibitory factor (MIF) plays a pivotal role in the development of various inflammatory diseases. Here, we found that anti-mouse MIF antibody treatment reduced liver injury and inflammatory cell infiltration into the liver after injection of antigen-specific cytotoxic T lymphocytes into hepatitis B virus transgenic mice.
American Society for Microbiology