Immunological abnormality in C3H/HeJ mice with heritable inflammatory bowel disease
J Ni, S Chen, D Hollander - Cellular immunology, 1996 - Elsevier
To explore the immunological abnormality of a heritable inflammatory bowel disease
developed in a new substrain of C3H/HeJ mice, we examined the expression of integrins β7
and other cell adhesion molecules on normal and disease mice lymphocytes by flow
cytometry. We also examined the cytotoxicity of small intestinal intraepithelial lymphocytes to
epithelial cells and the proliferation and aggregation of intestinal lymphocytes. There are
several significant changes in the expression levels of α4 and αM290β7 integrins, CD11a …
developed in a new substrain of C3H/HeJ mice, we examined the expression of integrins β7
and other cell adhesion molecules on normal and disease mice lymphocytes by flow
cytometry. We also examined the cytotoxicity of small intestinal intraepithelial lymphocytes to
epithelial cells and the proliferation and aggregation of intestinal lymphocytes. There are
several significant changes in the expression levels of α4 and αM290β7 integrins, CD11a …