Ghrelin and immunity: a young player in an old field

VD Dixit, DD Taub - Experimental gerontology, 2005 - Elsevier
There is increasing evidence of the coupling of immune status to the metabolic system. The
communication between the state of systemic and cellular energy balance to immune
compartment is mediated via a complex array of cytokines, hormones and neuropeptides.
Ghrelin, a recently described orexigenic peptide hormone, is predominantly produced by the
stomach and functions as a positive regulator of the somatotropic axis and a peripheral
signal of negative energy balance. Apart from its well-studied metabolic effects, ghrelin also …