Proliferation and apoptosis within juvenile capillary hemangiomas

AJ Mancini, BR Smoller - The American journal of …, 1996 - journals.lww.com
Capillary hemangiomas (CH) are benign vascular neoplasms of childhood that undergo a
natural course of postnatal growth followed by spontaneous involution and often complete
regression. There are currently no established standards for the identification of the growth
phase of CH. We retrospectively examined 24 CH specimens for staining with MIB1, a
monoclonal antibody directed at the same proliferation-related antigen as Ki-67, and
antibody to bcl-2, a protooncogene product associated with inhibition of cellular apoptosis …