The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells
I Ringshausen, M Oelsner, C Bogner, C Peschel… - Leukemia, 2008 - nature.com
I Ringshausen, M Oelsner, C Bogner, C Peschel, T Decker
Leukemia, 2008•nature.comBased upon these preliminary observations, we hypothesize that reducing exposure to
platelet transfusions and stored platelet supernatant might yield better clinical outcomes in
acute leukemia in adults. This hypothesis will need to be assessed in larger randomized
trials. Washed, leukoreduced, ABO identical transfusions represent an inexpensive,
technically simple and low-risk treatment strategy worth further investigation in patients with
acute leukemia.
platelet transfusions and stored platelet supernatant might yield better clinical outcomes in
acute leukemia in adults. This hypothesis will need to be assessed in larger randomized
trials. Washed, leukoreduced, ABO identical transfusions represent an inexpensive,
technically simple and low-risk treatment strategy worth further investigation in patients with
acute leukemia.
Based upon these preliminary observations, we hypothesize that reducing exposure to platelet transfusions and stored platelet supernatant might yield better clinical outcomes in acute leukemia in adults. This hypothesis will need to be assessed in larger randomized trials. Washed, leukoreduced, ABO identical transfusions represent an inexpensive, technically simple and low-risk treatment strategy worth further investigation in patients with acute leukemia.
nature.com
