[HTML][HTML] Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase
H Sakaue, W Ogawa, M Matsumoto, S Kuroda… - Journal of Biological …, 1998 - ASBMB
Differentiation of adipocytes is an important aspect of energy homeostasis. Although the
transcriptional regulation of adipocyte differentiation is relatively well characterized, the
subsequent molecular events remain unclear. The activity of phosphoinositide (PI) 3-kinase
precipitated with antibodies to phosphotyrosine has now been shown to increase transiently
during adipocyte differentiation of 3T3-F442A and of 3T3-L1 cells. PI 3-kinase activity
precipitated with antibodies to insulin receptor substrate 1 (IRS1) and association of …
transcriptional regulation of adipocyte differentiation is relatively well characterized, the
subsequent molecular events remain unclear. The activity of phosphoinositide (PI) 3-kinase
precipitated with antibodies to phosphotyrosine has now been shown to increase transiently
during adipocyte differentiation of 3T3-F442A and of 3T3-L1 cells. PI 3-kinase activity
precipitated with antibodies to insulin receptor substrate 1 (IRS1) and association of …