Neural stem cell therapy and gastrointestinal biology

HM Young - Gastroenterology, 2005 - gastrojournal.org
There is enormous excitement about the potential of transplanted neural stem or progenitor
cells to replace CNS neurons and glial cells lost through injury (eg, spinal cord injury) or
disease (eg, Parkinson's or Huntington Disease). In fact, clinical trials involving the
implantation of fetal midbrain cells into the striatum of patients with Parkinson's disease have
been underway for over 5 years. A number of GI motility disorders are caused by damage to
the enteric nervous system (ENS), and stem and progenitor cell-based therapy also offers …