Neural stem cell transplantation rescues rectum function in the aganglionic rat
YL Dong, W Liu, YM Gao, RD Wu, YH Zhang… - Transplantation …, 2008 - Elsevier
BACKGROUND: Neural stem cell (NSC) transplantation is a promising tool for restoring the
nervous system in a variety of neurodegenerative disorders. The aim of this study was to
determine the potential of NSC transplantation as a therapeutic strategy for neuronal
replacement of the enteric nervous system of the rectum in an aganglionic rat. MATERIALS
AND METHODS: Rat central nervous system–derived NSCs (CNS-NSCs) obtained from the
cortex of the fetal brain (E16) were transplanted into the benzalkonium chloride (BAC) …
nervous system in a variety of neurodegenerative disorders. The aim of this study was to
determine the potential of NSC transplantation as a therapeutic strategy for neuronal
replacement of the enteric nervous system of the rectum in an aganglionic rat. MATERIALS
AND METHODS: Rat central nervous system–derived NSCs (CNS-NSCs) obtained from the
cortex of the fetal brain (E16) were transplanted into the benzalkonium chloride (BAC) …