[HTML][HTML] Clinical outcome of children with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia treated between 1995 and 2005
Journal of clinical oncology, 2010•ncbi.nlm.nih.gov
Purpose In a previous analysis of 326 children with Philadelphia chromosome (Ph)–positive
acute lymphoblastic leukemia (ALL) treated between 1986 and 1996, hematopoietic stem-
cell transplantation from HLA-matched related donors, but not from unrelated donors, offered
a superior outcome than chemotherapy alone. To evaluate the impact of recent
improvements in chemotherapy and transplantation, we performed a similar analysis on
patients treated in the following decade.
acute lymphoblastic leukemia (ALL) treated between 1986 and 1996, hematopoietic stem-
cell transplantation from HLA-matched related donors, but not from unrelated donors, offered
a superior outcome than chemotherapy alone. To evaluate the impact of recent
improvements in chemotherapy and transplantation, we performed a similar analysis on
patients treated in the following decade.
Abstract
Purpose
In a previous analysis of 326 children with Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL) treated between 1986 and 1996, hematopoietic stem-cell transplantation from HLA-matched related donors, but not from unrelated donors, offered a superior outcome than chemotherapy alone. To evaluate the impact of recent improvements in chemotherapy and transplantation, we performed a similar analysis on patients treated in the following decade.
ncbi.nlm.nih.gov
