BCL10 down-regulation in peripheral T-cell lymphomas
M Rossi, C Agostinelli, S Righi, E Sabattini, F Bacci… - Human pathology, 2012 - Elsevier
The BCL10 gene encodes for a T-cell receptor signaling downstream protein involved in
nuclear factor κB activation. It is expressed in normal lymphoid tissues and in several B-non
Hodgkin lymphomas, its aberrant function being related to the pathogenesis of certain
subtypes. Conversely, conflicting data are available concerning BCL10 expression in
peripheral T cell lymphomas. We analyzed BCL10 expression in peripheral T cell
lymphomas and correlated it with NFκB activation, proliferation, phenotypic aberration, and …
nuclear factor κB activation. It is expressed in normal lymphoid tissues and in several B-non
Hodgkin lymphomas, its aberrant function being related to the pathogenesis of certain
subtypes. Conversely, conflicting data are available concerning BCL10 expression in
peripheral T cell lymphomas. We analyzed BCL10 expression in peripheral T cell
lymphomas and correlated it with NFκB activation, proliferation, phenotypic aberration, and …
