Expression and function of Toll-like receptors on dendritic cells and other antigen presenting cells from non-human primates
C Ketloy, A Engering, U Srichairatanakul… - Veterinary immunology …, 2008 - Elsevier
Antigen presenting cells (APCs), especially dendritic cells (DCs), play a crucial role in
immune responses against infections by sensing microbial invasion through Toll-like
receptors (TLRs). In this regard, TLR ligands are attractive candidates for use in humans and
animal models as vaccine adjuvants. So far, no studies have been performed on TLR
expression in non-human primates such as rhesus macaques. Therefore, we studied the
TLR expression patterns in different subsets of APC in rhesus macaques and compared …
immune responses against infections by sensing microbial invasion through Toll-like
receptors (TLRs). In this regard, TLR ligands are attractive candidates for use in humans and
animal models as vaccine adjuvants. So far, no studies have been performed on TLR
expression in non-human primates such as rhesus macaques. Therefore, we studied the
TLR expression patterns in different subsets of APC in rhesus macaques and compared …