[PDF][PDF] The lymphopenic mouse in immunology: from patron to pariah
NJ Singh, RH Schwartz - Immunity, 2006 - cell.com
NJ Singh, RH Schwartz
Immunity, 2006•cell.comCommentary The Lymphopenic Mouse in Immunology: From Patron to Pariah Page 1 Immunity
25, 851–855, December 2006 ©2006 Elsevier Inc. DOI 10.1016/j.immuni.2006.12.002
Commentary The Lymphopenic Mouse in Immunology: From Patron to Pariah Nevil J. Singh1
and Ronald H. Schwartz1,* 1 Laboratory of Cellular and Molecular Immunology National
Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 4 / 111 Center
Drive, MSC-0420 Bethesda, Maryland 20892 Summary A recent surge of interest in the behavior …
25, 851–855, December 2006 ©2006 Elsevier Inc. DOI 10.1016/j.immuni.2006.12.002
Commentary The Lymphopenic Mouse in Immunology: From Patron to Pariah Nevil J. Singh1
and Ronald H. Schwartz1,* 1 Laboratory of Cellular and Molecular Immunology National
Institute of Allergy and Infectious Diseases (NIAID) National Institutes of Health 4 / 111 Center
Drive, MSC-0420 Bethesda, Maryland 20892 Summary A recent surge of interest in the behavior …
Summary
A recent surge of interest in the behavior of T and B cells in lymphopenic model systems has resurrected a certain cynicism about the validity of using such models to answer important immunological questions. Here we discuss this skepticism in a broader historical context.
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