Tribromoethanol (Avertin) as an anaesthetic in mice
J Weiss, F Zimmermann - Laboratory Animals, 1999 - journals.sagepub.com
Tribromoethanol (Avertin) as an anaesthetic in mice Page 1 Letters to the Editor Tribromoethanol
(Avertin) as an anaesthetic in mice Zeller et a1. (1998) have described the 'adverse effects of
tribromoethanol as used in the production of transgenic mice'. The authors reported focal to
diffuse necrosis of the abdominal wall and necrotic changes on the surfaces of the abdominal
organs and concluded that the use of tribromoethanol is not to be recommended as a mouse
anaesthetic agent. For several reasons we disagree with their conclusion. Tribromoethanol …
(Avertin) as an anaesthetic in mice Zeller et a1. (1998) have described the 'adverse effects of
tribromoethanol as used in the production of transgenic mice'. The authors reported focal to
diffuse necrosis of the abdominal wall and necrotic changes on the surfaces of the abdominal
organs and concluded that the use of tribromoethanol is not to be recommended as a mouse
anaesthetic agent. For several reasons we disagree with their conclusion. Tribromoethanol …