Microbial infection and the septic response in critical surgical illness: Sepsis, not infection, determines outcome
J Marshall, D Sweeney - Archives of Surgery, 1990 - jamanetwork.com
• The differential roles ofinfectionas a microbial phenomenon andsepsisas a host response
were studied in 210 critically ill surgical patients. Infections occurred In 41.4% of all cases
and In 82% of nonsurviving patients. Both infection and the expression of a septic response,
measured as a sepsis score, were associated with significantly increased Intensive care unit
morbidity and mortality. Nonsurviving patients with infection had significantly higher sepsis
scores than did survivors. Nonsurvivors with sepsis, on the other hand, did not differ from …
were studied in 210 critically ill surgical patients. Infections occurred In 41.4% of all cases
and In 82% of nonsurviving patients. Both infection and the expression of a septic response,
measured as a sepsis score, were associated with significantly increased Intensive care unit
morbidity and mortality. Nonsurviving patients with infection had significantly higher sepsis
scores than did survivors. Nonsurvivors with sepsis, on the other hand, did not differ from …