Phosphatonins: a new class of phosphate-regulating proteins
SC Schiavi, OW Moe - Current opinion in nephrology and …, 2002 - journals.lww.com
SC Schiavi, OW Moe
Current opinion in nephrology and hypertension, 2002•journals.lww.comThe phosphatonins are a growing family of substances that may act on multiple organs in
autocrine, paracrine, and endocrine modes to regulate phosphate metabolism. As this list
expands, the need for a more rigid definition of the term phosphatonin becomes evident. The
identification and characterization of these phosphate-regulatory compounds will provide a
clearer understanding of how individual phosphatonins regulate phosphate in normal and
disease physiology. a Applied Genomics, Genzyme Corporation, One Mountain Road …
autocrine, paracrine, and endocrine modes to regulate phosphate metabolism. As this list
expands, the need for a more rigid definition of the term phosphatonin becomes evident. The
identification and characterization of these phosphate-regulatory compounds will provide a
clearer understanding of how individual phosphatonins regulate phosphate in normal and
disease physiology. a Applied Genomics, Genzyme Corporation, One Mountain Road …
Summary
The phosphatonins are a growing family of substances that may act on multiple organs in autocrine, paracrine, and endocrine modes to regulate phosphate metabolism. As this list expands, the need for a more rigid definition of the term phosphatonin becomes evident. The identification and characterization of these phosphate-regulatory compounds will provide a clearer understanding of how individual phosphatonins regulate phosphate in normal and disease physiology.
a Applied Genomics, Genzyme Corporation, One Mountain Road, Framingham, Massachusetts 01701; b Center of Mineral Metabolism and Clinical Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, and c Department of Veterans Affairs Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-8856, USA
Lippincott Williams & Wilkins