Evidence that NPY Y1 receptors are involved in stimulation of feeding by orexins (hypocretins) in sated rats
MR Jain, TL Horvath, PS Kalra, SP Kalra - Regulatory peptides, 2000 - Elsevier
Neuropeptide Y (NPY) produced in the arcuate nucleus (ARC) of the hypothalamus
stimulates feeding both directly by activating NPY receptors and indirectly through release of
the orexigenic peptides, galanin and β-endorphin (β-END), in the paraventricular nucleus
(PVN) and surrounding neural sites. Orexin A and orexin B, produced outside the ARC in the
lateral hypothalamic area (LH), have recently been shown to stimulate feeding. In the
present studies we tested the hypothesis that NPYergic signaling may mediate feeding …
stimulates feeding both directly by activating NPY receptors and indirectly through release of
the orexigenic peptides, galanin and β-endorphin (β-END), in the paraventricular nucleus
(PVN) and surrounding neural sites. Orexin A and orexin B, produced outside the ARC in the
lateral hypothalamic area (LH), have recently been shown to stimulate feeding. In the
present studies we tested the hypothesis that NPYergic signaling may mediate feeding …
