Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7: Ca2+-permeable cation channel that is constitutively …
T Okada, R Inoue, K Yamazaki, A Maeda… - Journal of Biological …, 1999 - ASBMB
Characterization of mammalian homologues ofDrosophila transient receptor potential
protein (TRP) is an important clue to understand molecular mechanisms underlying Ca 2+
influx activated in response to stimulation of G q protein-coupled receptors in vertebrate
cells. Here we have isolated cDNA encoding a novel seventh mammalian TRP homologue,
TRP7, from mouse brain. TRP7 showed abundant RNA expression in the heart, lung, and
eye and moderate expression in the brain, spleen, and testis. TRP7 recombinantly …
protein (TRP) is an important clue to understand molecular mechanisms underlying Ca 2+
influx activated in response to stimulation of G q protein-coupled receptors in vertebrate
cells. Here we have isolated cDNA encoding a novel seventh mammalian TRP homologue,
TRP7, from mouse brain. TRP7 showed abundant RNA expression in the heart, lung, and
eye and moderate expression in the brain, spleen, and testis. TRP7 recombinantly …