The amino acid sequence of a 27-residue peptide feleased from the α-chain carboxy-terminus during the plasmic digestion of human fibrinogen
BA Cottrell, RF Doolittle - Biochemical and Biophysical Research …, 1976 - Elsevier
BA Cottrell, RF Doolittle
Biochemical and Biophysical Research Communications, 1976•ElsevierThe amino acid sequence of a 27-residue peptide released during the early stages of the
plasmin digestion of human fibrinogen has been determined. The corresponding cyanogen
bromide fragment has also been isolated from the purified α-chains of fibrinogen, although a
separable fraction of those chains lack the fragment, evidently because of in vivo
degradation. The peptide is the carboxy-terminal segment of native α-chains.
plasmin digestion of human fibrinogen has been determined. The corresponding cyanogen
bromide fragment has also been isolated from the purified α-chains of fibrinogen, although a
separable fraction of those chains lack the fragment, evidently because of in vivo
degradation. The peptide is the carboxy-terminal segment of native α-chains.
The amino acid sequence of a 27-residue peptide released during the early stages of the plasmin digestion of human fibrinogen has been determined. The corresponding cyanogen bromide fragment has also been isolated from the purified α-chains of fibrinogen, although a separable fraction of those chains lack the fragment, evidently because of in vivo degradation. The peptide is the carboxy-terminal segment of native α-chains.
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