Lysogenization of Salmonella choleraesuis by phage 14 increases average length of O-antigen chains, serum resistance and intraperitoneal mouse virulence

NA Nnalue, S Newton, BAD Stocker - Microbial pathogenesis, 1990 - Elsevier
Three clones from a strain of Salmonella choleraesuis (serogroup C 1) were lysogenized
with phage 14 (P14) which converts the O-antigen of serogroup C 1 salmonellae from O-6, 7
to O-6, 7, 14. The lysogens were compared with their parental non-lysogenic clones with
respect to the following properties: average length of O-antigen polysaccharide chains,
sensitivity to normal human serum, and mouse-virulence. SDS-polyacrylamide gel
electrophoresis of lipopolysaccharides extracted from these bacteria showed that samples …