A new typhoid vaccine composed of the Vi capsular polysaccharide

SA Plotkin, N Bouveret-Le Cam - Archives of internal medicine, 1995 - jamanetwork.com
Typhoid is still prevalent in many parts of the world. We reviewed all published and
unpublished studies of a newly licensed vaccine composed of the Vi capsular
polysaccharide ofSalmonella typhi, the causative agent of the disease, which had been
licensed previously outside the United States. These included observational studies and
double-blind randomized studies done in the United States, Europe, and the developing
world in which children and adults unexposed to typhoid or those living in endemic areas …