Characterization of the phylogenetic distribution and chromosomal insertion sites of five IS6110elements inMycobacterium tuberculosis: non-random integration in …
NE Kurepina, S Sreevatsan, BB Plikaytis… - Tubercle and Lung …, 1998 - Elsevier
Setting: Five IS6110chromosomal insertion sites were characterized in the multidrug
resistantMycobacterium tuberculosis 'W'strain. Objective: To use insertion site probes to
study the phylogenetic distribution of IS610in theM. tuberculosisgenome. Design: A total of
722 M. tuberculosis isolates, previously genotyped using the standard IS610Southern blot
hybridization methodology, were re-hybridized with the Region A insertion site probe and
representative strains were further hybridized with the Region B and C probes. Strains were …
resistantMycobacterium tuberculosis 'W'strain. Objective: To use insertion site probes to
study the phylogenetic distribution of IS610in theM. tuberculosisgenome. Design: A total of
722 M. tuberculosis isolates, previously genotyped using the standard IS610Southern blot
hybridization methodology, were re-hybridized with the Region A insertion site probe and
representative strains were further hybridized with the Region B and C probes. Strains were …
