Origin and interstate spread of a New York City multidrug-resistant Mycobacterium tuberculosis clone family
Objective.—To determine whether isolates ofMycobacterium tuberculosisfrom New York and
elsewhere that are resistant to four or more primary antimicrobial agents and responsible for
widespread disease in the 1990s represent a newly emerged clone or a heterogeneous
array of unrelated organisms. Setting.—New York City area and selected locations in the
United States. Patients.—M tuberculosisisolates from 1953 patients in New York and
multidrug-resistant isolates from six patients from other US communities. Design …
elsewhere that are resistant to four or more primary antimicrobial agents and responsible for
widespread disease in the 1990s represent a newly emerged clone or a heterogeneous
array of unrelated organisms. Setting.—New York City area and selected locations in the
United States. Patients.—M tuberculosisisolates from 1953 patients in New York and
multidrug-resistant isolates from six patients from other US communities. Design …
